BDBM309387 (S)-N-(1-((6-(4-(4-fluorophenoxy)phenyl)pyridin-2-yl)amino)-3-(1-methyl-1H-imidazol-4-yl)-1-oxopropan-2-yl)cyclopropanecarboxamide::US9656959, Example 85

SMILES Cn1cnc(C[C@H](NC(=O)C2CC2)C(=O)Nc2cccc(n2)-c2ccc(Oc3ccc(F)cc3)cc2)c1

InChI Key InChIKey=ZECFTVLPBBHBSU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 309387   

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM309387(US9656959, Example 85 | (S)-N-(1-((6-(4-(4-fluorop...)
Affinity DataIC50: 111nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2019
Entry Details
US Patent