BDBM309475 US9603833, Example 87

SMILES CC(=O)N1CCN(CC1)c1ccc(CCc2ccc(CC(=O)NN)cc2)nc1

InChI Key InChIKey=MZMLXSFLDADQLO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 309475   

TargetAmine oxidase [copper-containing] 3(Human)
R-Tech Ueno

US Patent
LigandPNGBDBM309475(US9603833, Example 87)
Affinity DataIC50: 3.20nMAssay Description:The compounds of the present invention obtained in Production Examples were examined for the inhibitory effect on human and rat VAP-1 enzyme (SSAO) b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetMembrane primary amine oxidase(Rat)
R-Tech Ueno

US Patent
LigandPNGBDBM309475(US9603833, Example 87)
Affinity DataIC50: 1.40nMAssay Description:The compounds of the present invention obtained in Production Examples were examined for the inhibitory effect on human and rat VAP-1 enzyme (SSAO) b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
R-Tech Ueno

US Patent
LigandPNGBDBM309475(US9603833, Example 87)
Affinity DataIC50: 1.00E+5nMAssay Description:The compounds of the present invention obtained in the Production Examples were examined for the inhibitory effect on human monoamineoxydase enzymes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetAmine oxidase [flavin-containing] B(Human)
R-Tech Ueno

US Patent
LigandPNGBDBM309475(US9603833, Example 87)
Affinity DataIC50: 1.00E+5nMAssay Description:The compounds of the present invention obtained in the Production Examples were examined for the inhibitory effect on human monoamineoxydase enzymes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent