BDBM309484 US9603833, Example 105

SMILES NNC(=O)Cc1ccc(CCc2ccnc(c2)N2CCNCC2)cc1

InChI Key InChIKey=FMQLPQHGUVBUCF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 309484   

TargetMembrane primary amine oxidase(Rat)
R-Tech Ueno

US Patent
LigandPNGBDBM309484(US9603833, Example 105)
Affinity DataIC50: 7.20nMAssay Description:The compounds of the present invention obtained in Production Examples were examined for the inhibitory effect on human and rat VAP-1 enzyme (SSAO) b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetAmine oxidase [copper-containing] 3(Human)
R-Tech Ueno

US Patent
LigandPNGBDBM309484(US9603833, Example 105)
Affinity DataIC50: 7.30nMAssay Description:The compounds of the present invention obtained in Production Examples were examined for the inhibitory effect on human and rat VAP-1 enzyme (SSAO) b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetAmine oxidase [flavin-containing] B(Human)
R-Tech Ueno

US Patent
LigandPNGBDBM309484(US9603833, Example 105)
Affinity DataIC50: 1.00E+5nMAssay Description:The compounds of the present invention obtained in the Production Examples were examined for the inhibitory effect on human monoamineoxydase enzymes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetAmine oxidase [flavin-containing] A(Human)
R-Tech Ueno

US Patent
LigandPNGBDBM309484(US9603833, Example 105)
Affinity DataIC50: 1.00E+5nMAssay Description:The compounds of the present invention obtained in the Production Examples were examined for the inhibitory effect on human monoamineoxydase enzymes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent