BDBM309984 2-(5-((4-Chlorobenzyl)(cyclopropylmethyl)amino)-3-methoxypicolinoyl)cyclopropanecarboxylic acid::US9657001, 13

SMILES COc1cc(cnc1C(=O)C1CC1C(O)=O)N(CC1CC1)Cc1ccc(Cl)cc1

InChI Key InChIKey=JWNHRFABLXTBBS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 309984   

TargetLeukotriene C4 synthase(Human)
Astrazeneca

US Patent
LigandPNGBDBM309984(US9657001, 13 | 2-(5-((4-Chlorobenzyl)(cyclopropyl...)
Affinity DataIC50: 34nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent