BDBM310355 (2S,3R)—N-(4-(2,6-dimethoxyphenyl)-5-((2R)-1,4-dioxan-2-yl)-4H-1,2,4-triazol-3-yl)-3-(5-methoxy-2-pyrimidinyl)-2-butanesulfonamide or (2S,3R)—N-(4-(2,6-dimethoxyphenyl)-5-((2S)-1,4-dioxan-2-yl)-4H-1,2,4-triazol-3-yl)-3-(5-methoxy-2-pyrimidinyl)-2-butanesulfonamide::US10150760, Example 175.0::US10150760, Example 176.0

SMILES COc1cnc(nc1)[C@@H](C)[C@H](C)S(=O)(=O)Nc1nnc([C@@H]2COCCO2)n1-c1c(OC)cccc1OC

InChI Key InChIKey=FFPBTBGQFZVWPM-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 310355   

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM310355(US10150760, Example 175.0 | (2S,3R)—N-(4-(2,6...)
Affinity DataEC50:  3.5nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV-3 expression vector (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM310355(US10150760, Example 175.0 | (2S,3R)—N-(4-(2,6...)
Affinity DataEC50:  34nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV-3 expression vector (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent