BDBM310885 6-methyl-4-[4-(pyrrolidine-1-carbonyl)phenyl]-1H-pyrrolo[2,3-c]pyridin-7-one::US10150767, Example 29

SMILES Cn1cc(-c2ccc(cc2)C(=O)N2CCCC2)c2cc[nH]c2c1=O

InChI Key InChIKey=XQVXZFLEBIOLOZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 310885   

TargetBromodomain-containing protein 4 [42-168](Human)
Genentech

US Patent
LigandPNGBDBM310885(US10150767, Example 29 | 6-methyl-4-[4-(pyrrolidin...)
Affinity DataIC50: 280nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent