BDBM310945 US10155722, Example 27

SMILES CC(NC(=O)C1CC1)c1ccc(-c2ccsc2)c(NC(=O)Nc2cccc(c2)C(F)(F)F)c1

InChI Key InChIKey=DOCKODGUHFMYFN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 310945   

TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM310945(US10155722, Example 27)
Affinity DataIC50: 82.9nMAssay Description:The inhibitory activity of a compound against IDH2 (R172K, 40-end) was determined by the decrease of a helper factor NADPH. The test compound was pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent