BDBM31143 5-hydroxy-1H-indole-3-carboxylate, 22

SMILES CCOC(=O)c1c(Cc2cccc(Cl)c2)[nH]c2cc(c(O)cc12)-c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=PWQHMKJWBGSHBA-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31143   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Friedrich Alexander University Erlangen

LigandPNGBDBM31143(5-hydroxy-1H-indole-3-carboxylate, 22)
Affinity DataIC50: 330nM EC50:  2.80E+3nMAssay Description:For determination of the activity of 5-LO in 40000g supernatant (S40), aliquots of the supernatants were added to reaction mix, and were preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed