BDBM311787 7-Chloro-5-(7-(difluoromethyl)-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-8-yl)indolin-2-one::US10155769, Example 25

SMILES FC(F)c1ccn2nc(nc2c1-c1cc2CC(=O)Nc2c(Cl)c1)C(F)(F)F

InChI Key InChIKey=XVKHARRKJAULOT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311787   

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM311787(US10155769, Example 25 | 7-Chloro-5-(7-(difluorome...)
Affinity DataIC50: 0.631nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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