BDBM31190 US20240342139, Compound BL-1055::thiazol-2-amine, 1

SMILES Nc1nc(cs1)-c1ccccc1

InChI Key InChIKey=PYSJLPAOBIGQPK-UHFFFAOYSA-N

Data  3 IC50  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 31190   

TargetRunt-related transcription factor 1(Human)
University of Virginia At Charlottesville

LigandPNGBDBM31190(thiazol-2-amine, 1 | US20240342139, Compound BL-10...)
Affinity DatapH: 7.5 T: 2°CAssay Description:For the FRET measurements, the Cerulean-Runt (Runx1 41-190) and Venus-CBFbeta (1-141) fusion proteins were dialyzed into FRET assay buffer. Protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Boston College

Curated by ChEMBL
LigandPNGBDBM31190(thiazol-2-amine, 1 | US20240342139, Compound BL-10...)
Affinity DataIC50: 1.39E+6nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM31190(thiazol-2-amine, 1 | US20240342139, Compound BL-10...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant IDO expressed in Escherichia coli BL21 AIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetZinc finger CCCH domain-containing protein 14(Human)
Department of Veterans Affairs

US Patent
LigandPNGBDBM31190(thiazol-2-amine, 1 | US20240342139, Compound BL-10...)
Affinity DataIC50: 1.28E+5nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2025
Entry Details
Go to US Patent