BDBM312963 3′-[1-(2,3-Difluorobenzyl)-6-methyl-1H-pyrazolo[3,4-b]pyridin-3-yl]spiro[cyclopropane-1,7′-pyrrolo[2,3-e][1,2,4]triazin]-6′(5′H)-one::US9605008, 24

SMILES Cc1ccc2c(nn(Cc3cccc(F)c3F)c2n1)-c1nnc2c(NC(=O)C22CC2)n1

InChI Key InChIKey=GZLMBGOBOATBRU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312963   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM312963(US9605008, 24 | 3′-[1-(2,3-Difluorobenzyl)-6...)
Affinity DataIC50: 21nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
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