BDBM312984 US20260098060, Example 40

SMILES COc1cc(C[C@@H]2COc3ccc4cnc(F)cc4c3C(=O)N[C@H](C(=O)NCCc3cc(OC)no3)CC(=O)N(C)[C@@H](CC(C)C)C(=O)N(C)[C@H](CC(F)(F)F)C(=O)N2)nc(OC)c1

InChI Key InChIKey=SAMRCAVEPQCYLO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312984   

TargetCytochrome P450 3A4(Human)
Idorsia Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 312984BDBM312984(US20260098060, Example 40)
Affinity DataIC50: 7.10E+3nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent