BDBM313726 5-({2-[4-(5-Chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]-3-(1-methyl-1H-pyrazol-3-yl)propanoyl}amino)-3-fluoropyridine-2-carboxamide (racemate)::US10167280, Example 31

SMILES COc1cn(C(Cc2ccn(C)n2)C(=O)Nc2cnc(C(N)=O)c(F)c2)c(=O)cc1-c1cc(Cl)ccc1C#N

InChI Key InChIKey=DDOPLTPHURYTSG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 313726   

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM313726(US10167280, Example 31 | 5-({2-[4-(5-Chloro-2-cyan...)
Affinity DataIC50: 11nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM313726(US10167280, Example 31 | 5-({2-[4-(5-Chloro-2-cyan...)
Affinity DataIC50: 61nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent