BDBM313764 US10167285, Example 9

SMILES CC(C)NCCCN1C(Nc2cncnc12)Sc1c2Oc2ccc1I

InChI Key InChIKey=HIOJLHNHFWVJPM-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 313764   

TargetHeat shock protein HSP 90-alpha(Human)
Memorial Sloan-Kettering Cancer Center

US Patent
LigandPNGBDBM313764(US10167285, Example 9)
Affinity DataEC50:  16.1nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Memorial Sloan-Kettering Cancer Center

US Patent
LigandPNGBDBM313764(US10167285, Example 9)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Memorial Sloan-Kettering Cancer Center

US Patent
LigandPNGBDBM313764(US10167285, Example 9)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent