BDBM314073 US10167313, Compound 71::Z-Asp-(D,L Ala(2'-quinolyl))-Val- Aspmethyl vinylsulfone

SMILES CC(C)[C@H](NC(=O)[C@@H](Cc1ccc2ccccc2n1)NC(=O)[C@H](CC(O)=O)NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC(O)=O)\C=C\S(C)(=O)=O

InChI Key InChIKey=XDTNISVZIRJASF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 314073   

TargetCaspase-3(Human)
Genesis Technologies

US Patent
LigandPNGBDBM314073(Z-Asp-(D,L Ala(2'-quinolyl))-Val- Aspmethyl vinyls...)
Affinity DataIC50: 100nMAssay Description:Selectivity of compound 55, compound 63, compound 48, compound 57, compound 88 toward caspase-1 (pro-inflammatory group), caspase-5 (group I), caspas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetCaspase-7(Human)
Genesis Technologies

US Patent
LigandPNGBDBM314073(Z-Asp-(D,L Ala(2'-quinolyl))-Val- Aspmethyl vinyls...)
Affinity DataIC50: 8.90E+3nMAssay Description:Selectivity of compound 55, compound 63, compound 48, compound 57, compound 88 toward caspase-1 (pro-inflammatory group), caspase-5 (group I), caspas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetCaspase-1(Human)
Genesis Technologies

US Patent
LigandPNGBDBM314073(Z-Asp-(D,L Ala(2'-quinolyl))-Val- Aspmethyl vinyls...)
Affinity DataIC50: 1.00E+4nMAssay Description:Selectivity of compound 55, compound 63, compound 48, compound 57, compound 88 toward caspase-1 (pro-inflammatory group), caspase-5 (group I), caspas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetCaspase-5(Human)
Genesis Technologies

US Patent
LigandPNGBDBM314073(Z-Asp-(D,L Ala(2'-quinolyl))-Val- Aspmethyl vinyls...)
Affinity DataIC50: 1.00E+4nMAssay Description:Selectivity of compound 55, compound 63, compound 48, compound 57, compound 88 toward caspase-1 (pro-inflammatory group), caspase-5 (group I), caspas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetCaspase-9(Human)
Genesis Technologies

US Patent
LigandPNGBDBM314073(Z-Asp-(D,L Ala(2'-quinolyl))-Val- Aspmethyl vinyls...)
Affinity DataIC50: 1.00E+4nMAssay Description:Selectivity of compound 55, compound 63, compound 48, compound 57, compound 88 toward caspase-1 (pro-inflammatory group), caspase-5 (group I), caspas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent