BDBM3146 2-pyridinone deriv. 52::5-ethyl-3-{[(5-ethyl-2-methoxy-4-methylphenyl)methyl]amino}-6-methyl-1,2-dihydropyridin-2-one

SMILES CCc1cc(CNc2cc(CC)c(C)[nH]c2=O)c(OC)cc1C

InChI Key InChIKey=CLSMMEOPBVDYIA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3146   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM3146(5-ethyl-3-{[(5-ethyl-2-methoxy-4-methylphenyl)meth...)
Affinity DataIC50: 33nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed