BDBM316354 cis-2-[2-(3-Chlorophenyl)-6-[3-[(3-methoxyazetidin-1-yl)methyl]cyclobutyl]-4-oxo-quinazolin-3-yl]-N-isopropyl-acetamide::US9617226, Example 35

SMILES COC1CN(C[C@H]2C[C@H](C2)c2ccc3nc(-c4cccc(Cl)c4)n(CC(=O)NC(C)C)c(=O)c3c2)C1

InChI Key InChIKey=JOTJJISHQATORQ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 316354   

TargetVasopressin V1a receptor(Human)
Abbvie Deutschland

US Patent
LigandPNGBDBM316354( cis-2-[2-(3-Chlorophenyl)-6-[3-[(3-methoxyazetidi...)
Affinity DataKi:  55nMAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)).The incub...More data for this Ligand-Target Pair
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Date in BDB:
5/8/2019
Entry Details
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