BDBM317138 3-Methyl-6-(2-(1-methyl-3-(pyrrolidin-1-yl)-1H-1,2,4-triazol-5-yl)ethyl)-2-(trifluoro-methyl)imidazo[1,2-b]pyridazine::US9617271, 1

SMILES Cc1c(nc2n1nc(cc2)CCc3nc(nn3C)N4CCCC4)C(F)(F)F

InChI Key InChIKey=KVWITRNYMQYSIA-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 317138   

LigandPNGBDBM317138(3-Methyl-6-(2-(1-methyl-3-(pyrrolidin-1-yl)-1H-1,2...)
Affinity DataIC50: 12nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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PDB3D3D Structure (crystal)