BDBM317481 4-(4-cyclobutoxy-5-(2- methylbenzo[d]oxazol-6-yl)-7H- pyrrolo[2,3-d]pyrimidin-2- ylamino)-3-methoxy-N-(oxetan- 3-yl)benzamide::US9623028, Compound 339

SMILES COc1cc(ccc1Nc1nc(OC2CCC2)c2c(c[nH]c2n1)-c1ccc2nc(C)oc2c1)C(=O)NC1COC1

InChI Key InChIKey=KXMLNXWIFJZEJN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 317481   

TargetDual specificity protein kinase CLK2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317481(US9623028, Compound 339 | 4-(4-cyclobutoxy-5-(2- m...)
Affinity DataIC50: 5.92nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317481(US9623028, Compound 339 | 4-(4-cyclobutoxy-5-(2- m...)
Affinity DataIC50: 7nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetDual specificity protein kinase CLK1(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317481(US9623028, Compound 339 | 4-(4-cyclobutoxy-5-(2- m...)
Affinity DataIC50: 526nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent