BDBM317496 7-{[(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)methyl]amino}-3,4-dihydro-2H-1,4-benzoxazin-3-one::US9624175, Compound I-11

SMILES Clc1ccc2[nH]c(=O)c(CNc3ccc4NC(=O)COc4c3)cc2c1

InChI Key InChIKey=WCLBHZCAEXTZLJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 317496   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Forma Therapeutics

US Patent
LigandPNGBDBM317496(US9624175, Compound I-11 | 7-{[(6-chloro-2-oxo-1,2...)
Affinity DataIC50: 5.50E+3nMAssay Description:Assays were performed in a 384-well black plate. An aliquot of 250 nL of compound was incubated with 10 μL of 30 nM IDH1-R132H or 10 nM IDH1-R13...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
Entry Details
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