BDBM319533 2-[6-(2- cyclopropyl- 1-oxo-2,3-dihydro- 1H-isoindol-5-yl)- 1,3-benzothiazol- 2-yl]-N- [(cyclopropyl- carbamoyl) methyl]-2-(2- ethoxyethane- sulfonyl)acetamide::US10173991, Example 596

SMILES COCCS(=O)(=O)C(C(=O)NCC(=O)NC1CC1)c1nc2ccc(cc2s1)-c1ccc2C(=O)N(Cc2c1)C1CC1

InChI Key InChIKey=ZLETZDUYEXPUHO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 319533   

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM319533(2-[6-(2- cyclopropyl- 1-oxo-2,3-dihydro- 1H-isoind...)
Affinity DataIC50: 2nMAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent