BDBM319828 US10174015, Compound 41

SMILES O=C(N1CCOC1=O)c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=ZCWCYFRLHJOVFC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 319828   

TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
Xiamen University

US Patent
LigandPNGBDBM319828(US10174015, Compound 41)
Affinity DataIC50: 680nMAssay Description:In the Experimental example, endocannabinoid hydrolases used were Fatty Acid Amide Hydrolase (FAAH) and N-acylethanolamide hydrolyzing acid amidase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetN-acylethanolamine-hydrolyzing acid amidase(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM319828(US10174015, Compound 41)
Affinity DataIC50: 680nMAssay Description:Inhibition of rat NAAA expressed in HEK293 cells using heptadecenoylethanolamide as substrate after 30 mins by HPLC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Xiamen University

US Patent
LigandPNGBDBM319828(US10174015, Compound 41)
Affinity DataIC50: 1.00E+5nMAssay Description:In the Experimental example, endocannabinoid hydrolases used were Fatty Acid Amide Hydrolase (FAAH) and N-acylethanolamide hydrolyzing acid amidase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent