BDBM320056 US10174016, Example 223

SMILES C[C@@H](NC(=O)c1cc(O[C@H]2CCN(C)C(C2)C(F)(F)F)cc(c1)-c1ncc(C)s1)c1cnc(nc1)C(F)(F)F

InChI Key InChIKey=ALJCLRFXPKVCLC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 320056   

TargetP2X purinoceptor 3(Human)
Beyer Aktiengesellschaft

US Patent
LigandPNGBDBM320056(US10174016, Example 223)
Affinity DataIC50: 3nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 2(Human)
Beyer Aktiengesellschaft

US Patent
LigandPNGBDBM320056(US10174016, Example 223)
Affinity DataIC50: 109nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent