BDBM320260 US10174020, Compound 8-1

SMILES OC(=O)c1cc2cc(NC(=O)[C@@H]3CCc4cc(cc(=O)n34)-c3cc(Cl)ccc3-n3cnnn3)ccc2[nH]1

InChI Key InChIKey=WZZLEVNLUGKSFY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 320260   

TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM320260(US10174020, Compound 8-1)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM320260(US10174020, Compound 8-1)
Affinity DataKi:  2nMAssay Description:The following method was used to test the in vitro inhibitory effect of the compounds of the present invention on the activity of human blood-coagula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
Go to US Patent