BDBM320532 4-(1-{[5-(1-Methyl-1H-pyrazol-4-yl)-7-(morpholin-4-yl)-3H-imidazo[4,5-b]pyridin-2-yl]carbonyl}piperidin-4-yl)morpholin-3-one::US10174035, Compound 77

SMILES Cn1cc(cn1)-c1cc(N2CCOCC2)c2nc([nH]c2n1)C(=O)N1CCC(CC1)N1CCOCC1=O

InChI Key InChIKey=AXIQWCZCRHUBRL-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 320532   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Daiichi Sankyo

US Patent

LigandBDBM320532(US10174035, Compound 77 | 4-(1-{[5-(1-Methyl-1H-py...)Copy SMILESCopy InChI

Affinity DataIC50: 9nMAssay Description:The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/16/2019
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL