BDBM320544 US10174035, Compound 87::[5-(1,3-Dimethyl-1H-pyrazol-4-yl)-6-fluoro-3-methyl-7-(morpholin-4-yl)-3H-imidazo[4,5-b]pyridin-2-yl][4-(morpholin-4-yl)piperidin-1-yl]methanone

SMILES Cc1nn(C)cc1-c1nc2n(C)c(nc2c(N2CCOCC2)c1F)C(=O)N1CCC(CC1)N1CCOCC1

InChI Key InChIKey=KSAUNTMEFRWCNM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 320544   

LigandPNGBDBM320544(US10174035, Compound 87 | [5-(1,3-Dimethyl-1H-pyra...)
Affinity DataIC50: 3nMAssay Description:The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

LigandPNGBDBM320544(US10174035, Compound 87 | [5-(1,3-Dimethyl-1H-pyra...)
Affinity DataIC50: 3nMAssay Description:The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM320544(US10174035, Compound 87 | [5-(1,3-Dimethyl-1H-pyra...)
Affinity DataIC50: 1.00E+4nMAssay Description:The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

LigandPNGBDBM320544(US10174035, Compound 87 | [5-(1,3-Dimethyl-1H-pyra...)
Affinity DataIC50: 1.00E+4nMAssay Description:The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM320544(US10174035, Compound 87 | [5-(1,3-Dimethyl-1H-pyra...)
Affinity DataIC50: 1.00E+4nMAssay Description:The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent