BDBM321394 6-[(E)-but-2-enyl]-4-[2-methoxy-5-(pyrrolidine-1-carbonyl)phenyl]-1H-pyrrolo[2,3-c]pyridin-7-one::US10183009, Example 68

SMILES COc1ccc(cc1-c1cn(C\C=C\C)c(=O)c2[nH]ccc12)C(=O)N1CCCC1

InChI Key InChIKey=CIHUPYCHSPJNJB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321394   

TargetBromodomain-containing protein 9 [134-239](Human)
Genentech

US Patent
LigandPNGBDBM321394(6-[(E)-but-2-enyl]-4-[2-methoxy-5-(pyrrolidine-1-c...)
Affinity DataIC50: 39nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent