BDBM3216 3-hydroxy-2-{[2-hydroxy-4-({[(1R,2R)-2-[(4-hydroxybenzene)amido]cyclopentyl]oxy}carbonyl)phenyl]carbonyl}benzoic acid::Modified Benzophenone Ring, Balanol Analog 16::trans-1-[4-(2-Carboxy-6-hydroxybenzoyl)-3-hydroxybenzoyloxy]-2-(4-hydroxybenzamido)cyclopentane

SMILES OC(=O)c1cccc(O)c1C(=O)c1ccc(cc1O)C(=O)O[C@@H]1CCC[C@H]1NC(=O)c1ccc(O)cc1

InChI Key InChIKey=AOKOQPGMOAIBCE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 3216   

LigandPNGBDBM3216(trans-1-[4-(2-Carboxy-6-hydroxybenzoyl)-3-hydroxyb...)
Affinity DataIC50: 350nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2005
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Sphinx Laboratories

LigandPNGBDBM3216(trans-1-[4-(2-Carboxy-6-hydroxybenzoyl)-3-hydroxyb...)
Affinity DataIC50: 2.60E+3nMAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Sphinx Laboratories

LigandPNGBDBM3216(trans-1-[4-(2-Carboxy-6-hydroxybenzoyl)-3-hydroxyb...)
Affinity DataIC50: 2.70E+3nMAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2005
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Sphinx Laboratories

LigandPNGBDBM3216(trans-1-[4-(2-Carboxy-6-hydroxybenzoyl)-3-hydroxyb...)
Affinity DataIC50: 4.30E+3nMAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2005
Entry Details Article
PubMed