BDBM3228 (3R,4R)-4-[(4-hydroxybenzene)amido]pyrrolidin-3-yl 3,5-dihydroxy-4-[(2-hydroxynaphthalen-1-yl)carbonyl]benzoate::Modified Benzophenone Ring, Balanol Analog 28::trans-4-[4-(2-Hydroxy-1-naphthoyl)-3,5-dihydroxybenzoyloxy]-3-(4-hydroxybenzamido)pyrrolidine

SMILES Oc1ccc(cc1)C(=O)N[C@@H]1CNC[C@H]1OC(=O)c1cc(O)c(C(=O)c2c(O)ccc3ccccc23)c(O)c1

InChI Key InChIKey=OMMPHCNBAQGWDC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 3228   

LigandPNGBDBM3228(trans-4-[4-(2-Hydroxy-1-naphthoyl)-3,5-dihydroxybe...)
Affinity DataIC50: 290nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2005
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Sphinx Laboratories

LigandPNGBDBM3228(trans-4-[4-(2-Hydroxy-1-naphthoyl)-3,5-dihydroxybe...)
Affinity DataIC50: 2.20E+3nMAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Sphinx Laboratories

LigandPNGBDBM3228(trans-4-[4-(2-Hydroxy-1-naphthoyl)-3,5-dihydroxybe...)
Affinity DataIC50: 5.60E+3nMAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2005
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Sphinx Laboratories

LigandPNGBDBM3228(trans-4-[4-(2-Hydroxy-1-naphthoyl)-3,5-dihydroxybe...)
Affinity DataIC50: 5.60E+3nMAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2005
Entry Details Article
PubMed