BDBM323603 6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl)phenoxy)-2-methylhexanoic acid ::US10188627, Compound 8o

SMILES CC(CCCCOc1ccccc1CN(C)C(=O)c1ccc(cc1)-c1ccco1)C(O)=O

InChI Key InChIKey=HASKDUVBSFNKIR-UHFFFAOYSA-N

Data  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 323603   

TargetPeroxisome proliferator-activated receptor delta(Human)
Mitobridge

US Patent
LigandPNGBDBM323603(6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl)phe...)
Affinity DataEC50:  229nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent

TargetPeroxisome proliferator-activated receptor delta(Human)
Mitobridge

US Patent
LigandPNGBDBM323603(6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl)phe...)
Affinity DataEC50:  1.64E+3nMAssay Description:Cell Handling: PathHunter NHR cell lines were expanded from freezer stocks according to standard procedures. Cells were seeded in a total volume of 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent

TargetPPAR delta protein(Rat)
Mitobridge

US Patent
LigandPNGBDBM323603(6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl)phe...)
Affinity DataEC50:  229nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent

TargetPeroxisome proliferator-activated receptor delta(Human)
Mitobridge

US Patent
LigandPNGBDBM323603(6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl)phe...)
Affinity DataEC50:  640nMAssay Description:Transactivation of yeast GAL4 DNA binding domain-fused PPARdelta LBD (unknown origin) expressed in CV-1 cells after 24 hrs by luciferase reporter gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM323603(6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl)phe...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human PPARalpha LBD expressed in CHO-K1 cells by beta galactosidase enzyme fragment complement based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Mitobridge

US Patent
LigandPNGBDBM323603(6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl)phe...)
Affinity DataEC50:  230nMAssay Description:Activation of human PPARdelta LBD expressed in CHO-K1 cells by beta galactosidase enzyme fragment complement based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM323603(6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl)phe...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human PPARgamma LBD expressed in CHO-K1 cells by beta galactosidase enzyme fragment complement based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed