BDBM32534 arylsulfonylpiperazine, 6

SMILES FC(F)(F)c1cccnc1N1CCN(CC1)S(=O)(=O)Cc1ccccc1

InChI Key InChIKey=PJPDEWCQEUIXFC-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 32534   

LigandPNGBDBM32534(arylsulfonylpiperazine, 6)
Affinity DataIC50: 20nM EC50:  574nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed
LigandPNGBDBM32534(arylsulfonylpiperazine, 6)
Affinity DataIC50: 47nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2009
Entry Details Article
PubMed