BDBM325603 1-Isopropyl-3-{5-[1-(tetrahydro-pyran-4-yl)-piperidin-4-yl]-[1,3,4]oxadiazol-2-yl}-1H-indazole ::US9636335, 48

SMILES CC(C)n1nc(-c2nnc(o2)C2CCN(CC2)C2CCOCC2)c2ccccc12

InChI Key InChIKey=KHBGKYWBBOIOEW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 325603   

Target5-hydroxytryptamine receptor 4(Human)
Suven Life Sciences

US Patent
LigandPNGBDBM325603(1-Isopropyl-3-{5-[1-(tetrahydro-pyran-4-yl)-piperi...)
Affinity DataEC50:  54nMAssay Description:A stable CHO cell line expressing recombinant human 5-HT4 receptor and pCRE-Luc reporter system was used for cell-based assay. The assay offers a non...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

Target5-hydroxytryptamine receptor 4(Human)
Suven Life Sciences

US Patent
LigandPNGBDBM325603(1-Isopropyl-3-{5-[1-(tetrahydro-pyran-4-yl)-piperi...)
Affinity DataEC50:  79nMAssay Description:Partial agonist activity at human 5HT4E receptor expressed in CHO cells assessed as cAMP accumulation incubated for 4 hrs by luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed