BDBM325995 4-(2-fluoro-4-methoxyphenyl)-7-[1-(2-methylpyrimidin-5-yl)propan-2(S)-yl]quinoline-2-carboxamide::US9636337, 8-10

SMILES COc1ccc(c(F)c1)-c1cc(nc2cc(ccc12)[C@@H](C)Cc1cnc(C)nc1)C(N)=O

InChI Key InChIKey=GOJDHJGOUFNSSC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 325995   

TargetMetabotropic glutamate receptor 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM325995(4-(2-fluoro-4-methoxyphenyl)-7-[1-(2-methylpyrimid...)
Affinity DataIC50: 7nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
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