BDBM32679 1,3-Dimethyl-10-oxo-10H-9-oxa-4-aza-phenanthrene-2-carboxylic acid ethyl ester::2,4-dimethyl-5-oxo-3-[1]benzopyrano[4,3-b]pyridinecarboxylic acid ethyl ester::5-keto-2,4-dimethyl-chromeno[4,3-b]pyridine-3-carboxylic acid ethyl ester::MLS000120905::SMR000118354::cid_766691::ethyl 2,4-dimethyl-5-oxidanylidene-chromeno[4,3-b]pyridine-3-carboxylate::ethyl 2,4-dimethyl-5-oxochromeno[4,3-b]pyridine-3-carboxylate

SMILES CCOC(=O)c1c(C)nc2c3ccccc3oc(=O)c2c1C

InChI Key InChIKey=CBBHEFALSKDVEG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 32679   

TargetCoagulation factor XI(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32679(ethyl 2,4-dimethyl-5-oxochromeno[4,3-b]pyridine-3-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetCoagulation factor XI(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32679(ethyl 2,4-dimethyl-5-oxochromeno[4,3-b]pyridine-3-...)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:Factor XIa (0.23 ug/mL) was incubated with Boc-Glu-Ala-Arg-AMC substrate (15 uM) in 10 uL of assay buffer for 2 hr at room temperature. Read fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2009
Entry Details
PCBioAssay