BDBM326828 US9662327, Compound 413

SMILES CCc1nc(N2CCN([C@@H](C2)C(C)C)C(=O)CCOC)c(C#N)c2CC(C)(C)OCc12

InChI Key InChIKey=XUMMKWJIMLIBAW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 326828   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Agios Pharmaceuticals

US Patent
LigandPNGBDBM326828(US9662327, Compound 413)
Affinity DataIC50: 500nMAssay Description:Assays were conducted in a volume of 76 μl assay buffer (150 mM NaCl, 10 mM MgCl2, 20 mM Tris pH 7.5, 0.03% bovine serum albumin) as follows in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent