BDBM329017 4-(5-chloro-6-((2S)-2-(1- methylethyl)-1-pyrrolidinyl)-3- pyridinyl)-3-methoxy-N- (methylsulfonyl)benzamide::4-(5-chloro-6-((2S)-2-(1-methylethyl)-1-pyrrolidinyl)-3-pyridinyl)-3-methoxy-N-(methylsulfonyl)benzamide::US9663508, Example 355

SMILES COc1cc(ccc1-c1cnc(N2CCC[C@H]2C(C)C)c(Cl)c1)C(=O)NS(C)(=O)=O

InChI Key InChIKey=POFCZXSWSQJBSJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 329017   

LigandPNGBDBM329017(US9663508, Example 355 | 4-(5-chloro-6-((2S)-2-(1-...)
Affinity DataIC50: 87.7nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent

LigandPNGBDBM329017(US9663508, Example 355 | 4-(5-chloro-6-((2S)-2-(1-...)
Affinity DataIC50: 88nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells incubated for 3 to 5 mins at -125 mV holding potential by electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
LigandPNGBDBM329017(US9663508, Example 355 | 4-(5-chloro-6-((2S)-2-(1-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells incubated for 3 to 5 mins at -50 mV holding potential by electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed