BDBM3295 4-Anilinoquinazoline deriv. 46::CHEMBL52197::N-(3-bromophenyl)-6-methoxyquinazolin-4-amine

SMILES COc1ccc2ncnc(Nc3cccc(Br)c3)c2c1

InChI Key InChIKey=LDTMDWOXHYGMAM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 3295   

TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3295(CHEMBL52197 | N-(3-bromophenyl)-6-methoxyquinazoli...)
Affinity DataIC50: 30nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3295(CHEMBL52197 | N-(3-bromophenyl)-6-methoxyquinazoli...)
Affinity DataIC50: 348nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3295(CHEMBL52197 | N-(3-bromophenyl)-6-methoxyquinazoli...)
Affinity DataIC50: 355nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed