BDBM3298 4-Anilinoquinazoline deriv. 49::CHEMBL93181::N-(3-bromophenyl)-7-methoxyquinazolin-4-amine

SMILES COc1ccc2c(Nc3cccc(Br)c3)ncnc2c1

InChI Key InChIKey=CDWGVMQLDOQALI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 3298   

TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM3298(N-(3-bromophenyl)-7-methoxyquinazolin-4-amine | CH...)
Affinity DataIC50: 10nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM3298(N-(3-bromophenyl)-7-methoxyquinazolin-4-amine | CH...)
Affinity DataIC50: 10nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM3298(N-(3-bromophenyl)-7-methoxyquinazolin-4-amine | CH...)
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2005
Entry Details Article
PubMed