BDBM330 (3R,4S,5S,6R)-2-benzyl-4,5-dihydroxy-7-methyl-3,6-bis(phenoxymethyl)-1,2,7-thiadiazepane-1,1-dione::(3R,4S,5S,6R)-3,6-Bis(phenoxymethyl)-4,5-dihydroxy-7-methyl-2-benzyl-1,2,7-thiadiazepine 1,1-Dioxide::Cyclic Sulfamide deriv. 8

SMILES CN1[C@H](COc2ccccc2)[C@H](O)[C@@H](O)[C@@H](COc2ccccc2)N(Cc2ccccc2)S1(=O)=O

InChI Key InChIKey=JGESUXRXNORBLL-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 330   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM330((3R,4S,5S,6R)-3,6-Bis(phenoxymethyl)-4,5-dihydroxy...)
Affinity DataKi:  510nM ΔG°:  -8.72kcal/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2004
Entry Details Article
PubMed