BDBM3312 4-N-[3-(trifluoromethyl)phenyl]pyrido[4,3-d]pyrimidine-4,7-diamine::7-Aminopyrido[4,3-d]pyrimidine 7i::7-amino-4-[[3-(trifluoromethyl)phenyl]amino]pyrido[4,3-d]pyrimidine

SMILES Nc1cc2ncnc(Nc3cccc(c3)C(F)(F)F)c2cn1

InChI Key InChIKey=UCCQIOAGMXPOET-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3312   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3312(7-amino-4-[[3-(trifluoromethyl)phenyl]amino]pyrido...)
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2005
Entry Details Article
PubMed