BDBM331845 3-N-(4-N-mPEG3-3,5-dimethylpiperazinyl) lamotrigine::US10189859, Compound 111

SMILES COCCOCCOCCN1C(C)CN(CC1C)c1nnc(Cl)c(N)n1

InChI Key InChIKey=YCQOLJSOLKCYTO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 331845   

TargetSodium channel protein type 9 subunit alpha(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM331845(US10189859, Compound 111 | 3-N-(4-N-mPEG3-3,5-dime...)
Affinity DataIC50: 2.00E+5nMAssay Description:The potencies of the compounds provided herein to block specific Na+ channels was measured using automated patch clamp electrophysiologically of Nav1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM331845(US10189859, Compound 111 | 3-N-(4-N-mPEG3-3,5-dime...)
Affinity DataIC50: 5.00E+4nMAssay Description:The potencies of the compounds provided herein to block specific Na+ channels was measured using automated patch clamp electrophysiologically of Nav1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent