BDBM331919 US10189859, Compound 55

SMILES CCOC[C@H](O)CN1CCN(CC1)c1nnc(c(N)n1)-c1cccc(Cl)c1Cl

InChI Key InChIKey=IWLGAVYSLLKTLJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 331919   

TargetSodium channel protein type 9 subunit alpha(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM331919(US10189859, Compound 55)
Affinity DataIC50: 2.00E+5nMAssay Description:The potencies of the compounds provided herein to block specific Na+ channels was measured using automated patch clamp electrophysiologically of Nav1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM331919(US10189859, Compound 55)
Affinity DataIC50: 6.23E+4nMAssay Description:The potencies of the compounds provided herein to block specific Na+ channels was measured using automated patch clamp electrophysiologically of Nav1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent