BDBM331939 6-(2,3-dichlorophenyl)-N3-(3-(2-(2-methoxyethoxy)ethoxy)-2-methylpropyl)-1,2,4-triazine-3,5-diamine::US10189859, Compound 177

SMILES COCCOCCOCC(C)CNc1nnc(c(N)n1)-c1cccc(Cl)c1Cl

InChI Key InChIKey=CTPNHLZJDJRQEO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 331939   

TargetSodium channel protein type 9 subunit alpha(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM331939(US10189859, Compound 177 | 6-(2,3-dichlorophenyl)-...)
Affinity DataIC50: 2.00E+5nMAssay Description:The potencies of the compounds provided herein to block specific Na+ channels was measured using automated patch clamp electrophysiologically of Nav1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM331939(US10189859, Compound 177 | 6-(2,3-dichlorophenyl)-...)
Affinity DataIC50: 5.00E+4nMAssay Description:The potencies of the compounds provided herein to block specific Na+ channels was measured using automated patch clamp electrophysiologically of Nav1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent