BDBM33206 thiazoloazepinyl acetamide, 5

SMILES CC(=O)Nc1nc2c(s1)C(=O)NCCC2

InChI Key InChIKey=OYHOEDBNAJPFKK-UHFFFAOYSA-N

Data  2 Other

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 33206   

TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

LigandPNGBDBM33206(thiazoloazepinyl acetamide, 5)
Affinity DatapH: 7.5 T: 2°CAssay Description:AlphaScreen (PerkinElmer Life Sciences, Inc) was performed in opaque 384-well polypropylene plates. The assay relies on hydrogel coated Donor and Acc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

LigandPNGBDBM33206(thiazoloazepinyl acetamide, 5)
Affinity DatapH: 7.5 T: 2°CAssay Description:CHK kinase function was measured in a DELFIA assay in order to monitor phosphorylation of a CDC25C peptide using a specific phospho antibody. The enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)