BDBM33233 thieno[2,3-d]pyrimidine, 21e

SMILES CCNC(=O)c1cc2c(nc(N)nc2s1)-c1ccc(Cl)cc1Cl

InChI Key InChIKey=YPEOXUOUTBMBCX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 33233   

TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM33233(thieno[2,3-d]pyrimidine, 21e)
Affinity DataIC50: 230nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2009
Entry Details Article
PubMed