BDBM332462 4-(1-(2-chloro-6- (trifluoromethyl) benzoyl)-6- (cyclopropyl(methyl) carbamoyl)-1H- pyrazolo[4,3- b]pyridin-3-yl)-3- fluorobenzoic acid::US10196354, Example 7D

SMILES OC(=O)c1ccc(-c2nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cc(cnc23)C(=O)NCC2CC2)c(F)c1

InChI Key InChIKey=LQXJLGVOQLFJTD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332462   

TargetNuclear receptor ROR-gamma(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM332462(US10196354, Example 7D | 4-(1-(2-chloro-6- (triflu...)
Affinity DataIC50: 14nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
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