BDBM332547 (2E)-3-(4-bromophenyl)-1-{7-[(3-bromophenyl)carbonyl]-2,7-diazaspiro[3.5]non-2-yl}prop-2-en-1-one::US10196369, Compound C2

SMILES Brc1ccc(\C=C\C(=O)N2CC3(C2)CCN(CC3)C(=O)c2cccc(Br)c2)cc1

InChI Key InChIKey=HVIJQLAUIZJYPF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332547   

TargetG-protein coupled receptor 183(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM332547(US10196369, Compound C2 | (2E)-3-(4-bromophenyl)-1...)
Affinity DataIC50: 5nMAssay Description:The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
Go to US Patent