BDBM332841 9-(cyclopropylsulfonyl)-3-(3,5-dimethyl-4-isoxazolyl)-6-(methylsulfonyl)-9H-carbazole-1-carboxamide::US10196387, Example 77

SMILES COC(=O)c1cc(cc2c3cc(ccc3n(c12)S(=O)(=O)C1CC1)S(C)(=O)=O)-c1c(C)noc1C

InChI Key InChIKey=RYFGEAFQZLBTIS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 332841   

TargetBromodomain-containing protein 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM332841(US10196387, Example 77 | 9-(cyclopropylsulfonyl)-3...)
Affinity DataIC50: 500nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2019
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM332841(US10196387, Example 77 | 9-(cyclopropylsulfonyl)-3...)
Affinity DataIC50: 500nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
Go to US Patent