BDBM333330 3-(((3-((2S,3R,4S)-3,4-dihydroxytetrahydrothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl)amino)methyl)benzonitrile::US10196396, Compound 141

SMILES O[C@@H]1CS[C@H]([C@@H]1O)c1cnc2c(NCc3cccc(c3)C#N)nccn12

InChI Key InChIKey=KXSVGWHFBRAHPT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333330   

TargetAdenosine receptor A3(Human)
Handok

US Patent
LigandPNGBDBM333330(US10196396, Compound 141 | 3-(((3-((2S,3R,4S)-3,4-...)
Affinity DataIC50: 55nMAssay Description:HEK-293 cell membrane homogenates (32 μg protein), in which A3 adenosine receptors were expressed, are incubated for 120 min at 22° C. with 0.15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2019
Entry Details
US Patent