BDBM333881 US9730940, Compound 1-34::tert-butyl (3S)-3-{[9-ethyl-8-(6- methoxy-5-methylpyridin-3-yl)- 9H-purin-6-yl]oxy}pyrrolidine- 1-carboxylate

SMILES CCn1c(nc2c(OC3CCN(C3)C(=O)OC(C)(C)C)ncnc12)-c1cnc(OC)c(C)c1

InChI Key InChIKey=WVFXHABTHMAMPN-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333881   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM333881(tert-butyl (3S)-3-{[9-ethyl-8-(6- methoxy-5-methyl...)Copy SMILESCopy InChI

Affinity DataIC50: 0.700nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/23/2019
Entry Details
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